MHY884
Code | Size | Price |
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TAR-T25807-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25807-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25807-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MHY884 is an inhibitor of tyrosinase that acts by inhibiting UVB-induced activation of the NF-κB signaling pathway through the downregulation of oxidative stress.
CAS:
1393371-35-1
Formula:
C15H14ClNO3S
Molecular Weight:
323.79
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1O)C1Nc2cc(Cl)ccc2S1
References
1. Choi YJ, Uehara Y, Park JY,et al. MHY884, a newly synthesized tyrosinase inhibitor, suppresses UVB-induced activation of NF-?B signaling pathway through the downregulation of oxidative stress. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1344-8. doi: 10.1016/j.bmcl.2014.01.040. Epub 2014 Jan 25. PubMed PMID: 24508132.
2. Ha YM, Uehara Y, Park D, Jeong HO, Park JY, Park YJ, Lee JY, Lee HJ, Song YM, Moon HR, Chung HY. Synthesis and preliminary in vitro biological evaluation of 5-chloro-2-(substituted phenyl)benzo[d]thiazole derivatives designed as novel antimelanogenesis agents. Appl Biochem Biotechnol. 2012 Nov;168(6):1416-33.