Monatepil maleate
| Code | Size | Price |
|---|
| TAR-T25828-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25828-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25828-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Monatepil maleate is an Antihypertensive agent. It is a calcium antagonist with alpha(1)-adrenergic receptor blocking activity
CAS:
132046-06-1
Formula:
C32H34FN3O5S
Molecular Weight:
591.7
Purity:
0.98
SMILES:
OC(=O)C=C/C(O)=O.Fc1ccc(cc1)N1CCN(CCCC(=O)NC2c3ccccc3CSc3ccccc23)CC1
References
1. Liu MH, Floten SH, Yang Q, He GW. Inhibition of vasoconstriction by AJ-2615, a novel calcium antagonist with alpha(1)-adrenergic receptor blocking activity in human conduit arteries used as bypass grafts. Br J Clin Pharmacol. 2001 Sep;52(3):279-87. PubMed PMID: 11560560; PubMed Central PMCID: PMC2014550.
2. Singh NK, Goyal RK. New classes of antihypertensive drugs: therapeutic potentials. Clin Exp Hypertens. 1999 Jan-Feb;21(1-2):137-43. Review. PubMed PMID: 10052649.
3. Ikeno A, Sumiya T, Minato H, Fujitani B, Masuda Y, Hosoki K, Kurono M, Yasuba M. Effects of monatepil maleate, a new Ca2+ channel antagonist with alpha1-adrenoceptor antagonistic activity, on cholesterol absorption and catabolism in high cholesterol diet-fed rabbits. Jpn J Pharmacol. 1998 Nov;78(3):303-12. PubMed PMID: 9869264.
4. Matsunaga A, Inoue T, Koga T, Mori K, Kugi M, Sasaki J, Arakawa K. Effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic blocking activity, on the low-density lipoprotein receptor in human skin fibroblasts. Cardiovasc Drugs Ther. 1997 Dec;11(6):747-50. PubMed PMID: 9512869.