NC 1100
| Code | Size | Price |
|---|
| TAR-T25854-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25854-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25854-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
NC 1100 is a calcium channel antagonist.
CAS:
93035-33-7
Formula:
C27H34Cl2N2O3
Molecular Weight:
505.48
Purity:
0.98
SMILES:
Cl.Cl.COc1ccc(cc1OC)C(O)CN1CCN(CC1)C(c1ccccc1)c1ccccc1
References
1. Miyake N, Takayanagi I. Stereoselectivity of NC-1100, a Ca-entry blocker. Gen Pharmacol. 1990;21(2):261-3. PubMed PMID: 2332145.
2. Matsumura T, Furuichi H, Izumi J, Kamatsuka Y, Takei M, Nakata N, Ito S, Suda H, Kizaki K, Kurimoto T. [Effects of NC-1100, a calcium channel blocker, on experimental cerebral ischemia/anoxia in rodents]. Nihon Yakurigaku Zasshi. 1993 Mar;101(3):177-86. Japanese. PubMed PMID: 8486322.
3. Sadoshima S, Ibayashi S, Nakane H, Okada Y, Ooboshi H, Fujishima M. Attenuation of ischemic and postischemic damage to brain metabolism and circulation by a novel Ca2+ channel antagonist, NC-1100, in spontaneously hypertensive rats. Eur J Pharmacol. 1992 Dec 2;224(2-3):109-15. PubMed PMID: 1468503.
4. Hashimoto T, Kimori M, Nakamura Y, Kuriyama K. Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone spontaneously hypertensive rat. Jpn J Pharmacol. 1989 Jun;50(2):131-9. PubMed PMID: 2770051.