Pbc 264
| Code | Size | Price |
|---|
| TAR-T25921-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pbc 264 is a CCK agonist.
CAS:
125236-85-3
Formula:
C51H67N9O14S
Molecular Weight:
1072.25
Purity:
0.98
SMILES:
[3H]C([3H])([3H])C([3H])([3H])C(=O)N[C@@H](Cc1ccc(OS(O)(=O)=O)cc1)C(=O)N[C@@H](CCCC)NCC(=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
References
1. Durieux C, Ruiz-Gayo M, Roques BP. In vivo binding affinities of cholecystokinin agonists and antagonists determined using the selective CCKB agonist [3H]pBC 264. Eur J Pharmacol. 1991 Dec 17;209(3):185-93. PubMed PMID: 1797561.
2. Durieux C, Ruiz-Gayo M, Corringer PJ, Bergeron F, Ducos B, Roques BP. [3H]pBC 264, a suitable probe for studying cholecystokinin-B receptors: binding characteristics in rodent brains and comparison with [3H]SNF 8702. Mol Pharmacol. 1992 Jun;41(6):1089-95. PubMed PMID: 1614411.
3. Durieux C, Corringer PJ, Bergeron F, Roques BP. [3H]pBC 264, first highly potent and very selective radioligand for CCK-B receptors. Eur J Pharmacol. 1989 Sep 13;168(2):269-70. PubMed PMID: 2606153.
4. Ruiz-Gayo M, Durieux C, Fourni?-Zaluski MC, Roques BP. Stimulation of delta-opioid receptors reduces the in vivo binding of the cholecystokinin (CCK)-B-selective agonist [3H]pBC 264: evidence for a physiological regulation of CCKergic systems by endogenous enkephalins. J Neurochem. 1992 Nov;59(5):1805-11. PubMed PMID: 1357099.