p-DDAP
Code | Size | Price |
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TAR-T25925-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25925-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25925-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
p-DDAP is an anti-invasive agent that acts by significantly suppressing cell invasion, and the activity and mRNA expression of matrix metalloproteinase-9 (MMP-9).
CAS:
25848-37-7
Formula:
C18H31NO
Molecular Weight:
277.452
Purity:
0.98
SMILES:
CCCCCCCCCCCCNc1ccc(O)cc1
References
1. Takahashi N, Koyama S, Hasegawa S, Yamasaki M, Imai M. Anticancer efficacy of p-dodecylaminophenol against high-risk and refractory neuroblastoma cells in vitro and in vivo. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4664-4672. doi: 10.1016/j.bmcl.2017.09.005. Epub 2017 Sep 9. PubMed PMID: 28927789.
2. Takahashi N, Egawa R, Imai M, Takahashi K, Ohba T, Imaizumi M. The anti-tumor agent, p-DDAP potently suppresses proliferation through apoptosis in human neuroblastoma NB-39-nu cells. Cancer Lett. 2010 Nov 28;297(2):252-8. doi: 10.1016/j.canlet.2010.05.018. Epub 2010 Jun 26. PubMed PMID: 20580487.
3. Takahashi N, Fujiu Y. Effects of the aminophenol analogue p-Dodecylaminophenol on mouse skin. J Invest Dermatol. 2010 May;130(5):1258-67. doi: 10.1038/jid.2009.386. Epub 2009 Dec 24. PubMed PMID: 20032991.
4. Takahashi N, Watanabe Y, Maitani Y, Yamauchi T, Higashiyama K, Ohba T. p-Dodecylaminophenol derived from the synthetic retinoid, fenretinide: antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of action. Int J Cancer. 2008 Feb 1;122(3):689-98. PubMed PMID: 17955489.