Penasterol
| Code | Size | Price |
|---|
| TAR-T25930-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Penasterol suppresses IgE-dependent histamine release.
CAS:
116424-94-3
Formula:
C30H48O3
Molecular Weight:
456.711
Purity:
0.98
SMILES:
[H][C@@]12CCC3=C(CC[C@]4(C)[C@H](CC[C@@]34C(O)=O)[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2(C)C
References
1. Stead P, Hiscox S, Robinson PS, Pike NB, Sidebottom PJ, Roberts AD, Taylor NL, Wright AE, Pomponi SA, Langley D. Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity. Bioorg Med Chem Lett. 2000 Apr 3;10(7):661-4. PubMed PMID: 10762048.
2. Lyakhova EG, Kolesnikova SA, Kalinovsky AI, Dmitrenok PS, Nam NH, Stonik VA. Further study on Penares sp. from Vietnamese waters: minor lanostane and nor-lanostane triterpenes. Steroids. 2015 Apr;96:37-43. doi: 10.1016/j.steroids.2015.01.009. Epub 2015 Jan 29. PubMed PMID: 25637679.
3. Takei M, Umeyama A, Shoji N, Arihara S, Endo K. Mechanism of inhibition of IgE-dependent histamine release from rat mast cells by penasterol and penasterone. J Pharm Sci. 1995 Feb;84(2):228-30. PubMed PMID: 7537812.
4. Kubanek J, Fenical W, Pawlik JR. New antifeedant triterpene glycosides from the Caribbean sponge Erylus formosus. Nat Prod Lett. 2001;15(4):275-85. PubMed PMID: 11833623.