Phosalacine
Code | Size | Price |
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TAR-T25950-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.
CAS:
92567-89-0
Formula:
C14H28N3O6P
Molecular Weight:
365.367
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C(N)CCP(=O)CO)C(O)=O
References
1. Omura S, Murata M, Hanaki H, Hinotozawa K, Oiwa R, Tanaka H. Phosalacine, a new herbicidal antibiotic containing phosphinothricin. Fermentation, isolation, biological activity and mechanism of action. J Antibiot (Tokyo). 1984 Aug;37(8):829-35. PubMed PMID: 6480502.
2. Blodgett JA, Zhang JK, Yu X, Metcalf WW. Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products. J Antibiot (Tokyo). 2016 Jan;69(1):15-25. doi: 10.1038/ja.2015.77. Epub 2015 Sep 2. PubMed PMID: 26328935; PubMed Central PMCID: PMC4731264.
3. Omura S, Hinotozawa K, Imamura N, Murata M. The structure of phosalacine, a new herbicidal antibiotic containing phosphinothricin. J Antibiot (Tokyo). 1984 Aug;37(8):939-40. PubMed PMID: 6480509.
4. Werner WJ, Allen KD, Hu K, Helms GL, Chen BS, Wang SC. In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea. Biochemistry. 2011 Oct 25;50(42):8986-8. doi: 10.1021/bi201220r. Epub 2011 Sep 28. PubMed PMID: 21950770; PubMed Central PMCID: PMC3214642.