Phox-I1
Code | Size | Price |
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TAR-T25951-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25951-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25951-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.
CAS:
1388151-90-3
Formula:
C23H19N3O4
Molecular Weight:
401.422
Purity:
0.98
SMILES:
COc1ccc2OC(N3N=C(CC3c2c1)c1ccccc1)c1cccc(c1)[N+]([O-])=O
References
1. Bosco EE, Kumar S, Marchioni F, Biesiada J, Kordos M, Szczur K, Meller J, Seibel W, Mizrahi A, Pick E, Filippi MD, Zheng Y. Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. Chem Biol. 2012 Feb 24;19(2):228-42. doi: 10.1016/j.chembiol.2011.12.017. PubMed PMID: 22365606; PubMed Central PMCID: PMC3292765.
2. Jo H, Luo HR. Exploiting effectors of Rac GTPase. Chem Biol. 2012 Feb 24;19(2):169-71. doi: 10.1016/j.chembiol.2012.02.001. PubMed PMID: 22365599; PubMed Central PMCID: PMC3292760.