Poststatin
| Code | Size | Price |
|---|
| TAR-T25973-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3.
CAS:
135219-43-1
Formula:
C26H48N5O7
Molecular Weight:
542.698
Purity:
0.98
SMILES:
CCC(N)CC(=O)N(C(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)[C](=O)(CC(C)C)C(=O)N[C@@H](C(C)C)C(O)=O
References
1. Tsuda M, Muraoka Y, Someno T, Nagai M, Aoyagi T, Takeuchi T. Poststatin, a new inhibitor of prolyl endopeptidase. VI. Endopeptidase inhibitory activity of poststatin analogues containing pyrrolidine ring. J Antibiot (Tokyo). 1996 Sep;49(9):900-8. PubMed PMID: 8931724.
2. Tsuda M, Muraoka Y, Nagai M, Takeuchi T, Aoyagi T. Poststatin, a new inhibitor of prolyl endopeptidase. IV. The chemical synthesis of poststain. J Antibiot (Tokyo). 1996 Mar;49(3):287-91. PubMed PMID: 8626246.
3. Tsuda M, Muraoka Y, Nagai M, Aoyagi T, Takeuchi T. Poststatin, a new inhibitor of prolyl endopeptidase. VII. N-cycloalkylamide analogues. J Antibiot (Tokyo). 1996 Sep;49(9):909-20. PubMed PMID: 8931725.
4. Katori M, Majima M. Renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension. Prog Drug Res. 2014;69:59-109. Review. PubMed PMID: 25130040.