Promothiocin A
| Code | Size | Price |
|---|
| TAR-T25991-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Promothiocin A is an antibiotic.
CAS:
156737-05-2
Formula:
C36H37N11O8S2
Molecular Weight:
815.88
Purity:
0.98
SMILES:
CC(C)[C@@H]1NC(=O)c2csc(n2)-c2ccc(nc2-c2nc(oc2C)[C@H](C)NC(=O)c2csc(n2)[C@H](C)NC(=O)c2nc(CNC1=O)oc2C)C(=O)NC(=C)C(N)=O
References
1. Habazettl J, Allan M, Jensen PR, Sass HJ, Thompson CJ, Grzesiek S. Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5498-507. doi: 10.1073/pnas.1412070111. Epub 2014 Dec 8. PubMed PMID: 25489067; PubMed Central PMCID: PMC4280590.
2. Takagi M, Motohashi K, Nagai A, Hashimoto J, Shin-Ya K. JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19. J Antibiot (Tokyo). 2010 Jul;63(7):405-8. doi: 10.1038/ja.2010.66. Epub 2010 Jun 16. PubMed PMID: 20551986.
3. Yun BS, Hidaka T, Furihata K, Seto H. Promothiocins A and B novel thiopeptides with a tipA promoter inducing activity produced by Streptomyces sp. SF2741. J Antibiot (Tokyo). 1994 Apr;47(4):510-4. PubMed PMID: 8195055.