R 28935
| Code | Size | Price |
|---|
| TAR-T26013-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26013-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26013-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
R 28935 is a benzodioxan antihypertensive agent.
CAS:
55806-43-4
Formula:
C22H25N3O4
Molecular Weight:
395.459
Purity:
0.98
SMILES:
O[C@@H](CN1CCC(CC1)n1c2ccccc2[nH]c1=O)C1COc2ccccc2O1
References
1. Timmermans PB, Harms YM, Batink HD, Van Zwieten PA. Specific binding of threo 1-(1-[2-(1,4-benzodioxane-2-yl)-2-hydroxyethyl]4-piperidyl)-2-benzimidazolinone (R 29814), to rat brain membranes. Neuropharmacology. 1982 Oct;21(10):1039-43. PubMed PMID: 7145033.
2. Timmermans PB, Van Zwieten PA. Centrally induced impairment of the hypotensive effects of R 28935 and R 29814 by prazosin in anaesthetized cats. Eur J Pharmacol. 1980 Feb;61(4):385-8. PubMed PMID: 7053064.
3. Kwa HY, Timmermans PB, Van Zwieten PA. Interaction between prazosin and benzodioxan antihypertensives (R 28935 and R 29814); a competition for central alpha 1-adrenoceptors [proceedings]. Br J Pharmacol. 1980 Jan;68(1):138P-139P. PubMed PMID: 6244026; PubMed Central PMCID: PMC2044080.
4. Timmermans PB, Slothorst-Grisdijk FP, Kwa HY, van Zwieten PA. Inhibition of R 28935- and R 29814-induced hypotension by prazosin in anaesthetized normotensive rats. Arch Int Pharmacodyn Ther. 1982 Feb;255(2):309-20. PubMed PMID: 7073408.