Rioprostil
| Code | Size | Price |
|---|
| TAR-T26090-5mg | 5mg | £1,348.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26090-50mg | 50mg | £2,303.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26090-100mg | 100mg | £3,042.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rioprostil is a methyl prostaglandin E1 analog that decreases gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the treatment of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions.
CAS:
77287-05-9
Formula:
C21H38O4
Molecular Weight:
354.531
Purity:
0.98
SMILES:
CCCCC(C)(O)CC=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCCO
References
1. Cohen A, Tolman KG, Lewis GP, Brown S, van Horn A, McCormack GH, Simon DM. The antigastrolesive activity of rioprostil, a 16-methyl prostaglandin-E1 analogue in healthy volunteers. Scand J Gastroenterol Suppl. 1989;164:81-90; discussion 90-1. PubMed PMID: 2510286.
2. Boucekkine T, Meknini B, Bitoun A, Pruni?ras F, Khedis A, de Lauture D, Rotenberg A, Molinie C, Roux M, Gauthier A, et al. Treatment of duodenal ulcer with rioprostil: a randomized multicentre double-blind study. Scand J Gastroenterol Suppl. 1989;164:191-3. PubMed PMID: 2510266.
3. Fischer S, Schweer H, Kraft H, Weber P. Pharmacokinetics of rioprostil in human plasma as assayed by combined capillary gas chromatography-negative ion chemical ionization mass spectrometry. Scand J Gastroenterol Suppl. 1989;164:59-61; discussion 61-2. PubMed PMID: 2510282.
4. Corsing C, Demol P. Drug safety of rioprostil in patients with active gastric or duodenal ulcer. Scand J Gastroenterol Suppl. 1989;164:232-7; discussion 237-8. PubMed PMID: 2510274.