Ro 41-0960
Code | Size | Price |
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TAR-T26106-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26106-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26106-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 41-0960 is used as a reversible and orally-active COMT-inhibitor.
CAS:
125628-97-9
Formula:
C13H8FNO5
Molecular Weight:
277.207
Purity:
0.98
SMILES:
Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1ccccc1F
References
1. G?lvez-Llompart M, Recio MC, Garc?a-Domenech R, G?lvez J. Molecular topology: a strategy to identify novel compounds against ulcerative colitis. Mol Divers. 2017 Feb;21(1):219-234. doi: 10.1007/s11030-016-9706-7. Epub 2016 Oct 12. PubMed PMID: 27734189.
2. Gallardo E, Madrona A, Palma-Vald?s R, Espartero JL, Santiago M. Effect of intracerebral hydroxytyrosol and its nitroderivatives on striatal dopamine metabolism: A study by in vivo microdialysis. Life Sci. 2015 Aug 1;134:30-5. doi: 10.1016/j.lfs.2015.04.026. Epub 2015 May 30. PubMed PMID: 26032260.
3. Yang H, Ahn C, Jeung EB. Differential expression of calcium transport genes caused by COMT inhibition in the duodenum, kidney and placenta of pregnant mice. Mol Cell Endocrinol. 2015 Feb 5;401:45-55. doi: 10.1016/j.mce.2014.11.020. Epub 2014 Dec 5. PubMed PMID: 25486511.
4. Herndon JM, Cholanians AB, Lizarraga LE, Lau SS, Monks TJ. Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity. Toxicol Sci. 2014 May;139(1):162-73. doi: 10.1093/toxsci/kfu035. Epub 2014 Mar 3. PubMed PMID: 24591155; PubMed Central PMCID: PMC4007109.