Rohitukin
| Code | Size | Price |
|---|
| TAR-T26115-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rohitukin is a chromane alkaloid and a precursor of flavopiridol, a hopeful anti-cancer compound.
CAS:
62653-92-3
Formula:
C34H42O13
Molecular Weight:
658.697
Purity:
0.98
SMILES:
[H][C@]12CC(=O)OC[C@]1(C)OC(=O)C[C@H](OC(C)=O)[C@]2(C)[C@H]1[C@H](OC=O)[C@@H](OC(=O)CC(C)C)[C@@]2(C)[C@@H](CC(=O)[C@]2(O)C1=C)c1ccoc1
References
1. Sarker SD, Savchenko T, Whiting P, Sik V, Dinan L. Two limonoids from Turraea obtusifolia (Meliaceae), prieurianin and rohitukin, antagonise 20-hydroxyecdysone action in a Drosophila cell line. Arch Insect Biochem Physiol. 1997;35(1-2):211-7. PubMed PMID: 9131785.
2. Dzoyem JP, Tsamo AT, Melong R, Mkounga P, Nkengfack AE, McGaw LJ, Eloff JN. Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae). Biol Res. 2015 Oct 13;48:57. doi: 10.1186/s40659-015-0049-0. PubMed PMID: 26463660; PubMed Central PMCID: PMC4604621.
3. Mohanakumara P, Sreejayan N, Priti V, Ramesha BT, Ravikanth G, Ganeshaiah KN, Vasudeva R, Mohan J, Santhoshkumar TR, Mishra PD, Ram V, Shaanker RU. Dysoxylum binectariferum Hook.f (Meliaceae), a rich source of rohitukine. Fitoterapia. 2010 Mar;81(2):145-8. doi: 10.1016/j.fitote.2009.08.010. Epub 2009 Aug 15. PubMed PMID: 19686817.
4. Polonsky J, Varon Z, Marazano C, Arnoux B, Pettit GR, Schmid JM, Ochi M, Kotsuki H. The structure of amoorastatone and the cytotoxic limonoid 12-hydroxyamoorastatin. Experientia. 1979 Aug 15;35(8):987-9. PubMed PMID: 477905.