Rokitamycin
| Code | Size | Price |
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| TAR-T26116-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rokitamycin is a macrolide antibiotic produced from strains of Streptomyces kitasatoensis.
CAS:
74014-51-0
Formula:
C42H68NO16
Molecular Weight:
842.998
Purity:
0.98
SMILES:
CCCC(=O)O[C@H]1[C@@H](OC)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)[C@@H](O)C=CC=CC[C@@H](C)OC(=O)C1CCC([O-])=O
References
1. Kim JH, Lee YJ, Sohn HJ, Song KJ, Kwon D, Kwon MH, Im KI, Shin HJ. Therapeutic effect of rokitamycin in vitro and on experimental meningoencephalitis due to Naegleria fowleri. Int J Antimicrob Agents. 2008 Nov;32(5):411-7. doi: 10.1016/j.ijantimicag.2008.05.018. Epub 2008 Aug 30. PubMed PMID: 18762406.
2. Fukui M, Nagahara Y, Nishio Y, Honjoh T, Shinomiya T. Rokitamycin induces a mitochondrial defect and caspase-dependent apoptosis in human T-cell leukemia Jurkat cells. J Pharmacol Sci. 2009 May;110(1):69-77. Epub 2009 Apr 29. PubMed PMID: 19403997.
3. Gavini E, Rassu G, Ferraro L, Generosi A, Rau JV, Brunetti A, Giunchedi P, Dalpiaz A. Influence of chitosan glutamate on the in vivo intranasal absorption of rokitamycin from microspheres. J Pharm Sci. 2011 Apr;100(4):1488-502. doi: 10.1002/jps.22382. Epub 2010 Oct 29. PubMed PMID: 24081472.
4. Colombo U, Pifarotti G, Amidani M, Viezzoli T, Pifarotti P. [Rokitamycin in the treatment of female genital Chlamydia and Mycoplasma infections. Comparative study vs josamycin ]. Minerva Ginecol. 1998 Nov;50(11):491-7. Review. Italian. PubMed PMID: 9882991.