Ropizine
| Code | Size | Price |
|---|
| TAR-T26122-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26122-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26122-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ropizine is a benzhydryl piperazine that acts as an allosteric modifier to decreases the dissociation rate of [3H]DM so that can be used as an anticonvulsant.
CAS:
3601-19-2
Formula:
C24H26N4
Molecular Weight:
370.5
Purity:
0.98
SMILES:
Cc1cccc(C=NN2CCN(CC2)C(c2ccccc2)c2ccccc2)n1
References
1. Canoll PD, Smith PR, Musacchio JM. Ropizine concurrently enhances and inhibits [3H]dextromethorphan binding to different structures of the guinea pig brain: autoradiographic evidence for multiple binding sites. Life Sci. 1990;46(19):PL9-16. PubMed PMID: 2345483.
2. Edmonds HL Jr, Bellin SI, Chen FC, Hegreberg GA. Anticonvulsant properties of ropizine in epileptic and nonepileptic beagle dogs. Epilepsia. 1978 Apr;19(2):139-46. PubMed PMID: 639771.
3. Klein M, Musacchio JM. Computer-assisted analysis of dextromethorphan and (+)-3-(-3-hydroxyphenyl)-N-(1-propyl)piperidine binding sites in rat brain. Allosteric effects of ropizine. Life Sci. 1990;47(18):1625-34. PubMed PMID: 2250576.
4. Klein M, Musacchio JM. High-affinity dextromethorphan and (+)-3-(-3-hydroxyphenyl)-N-(1-propyl)piperidine binding sites in rat brain. Allosteric effects of ropizine. J Pharmacol Exp Ther. 1992 Mar;260(3):990-9. PubMed PMID: 1312173.