RTI 336
| Code | Size | Price |
|---|
| TAR-T26145-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26145-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26145-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
RTI 336 is used as a chronic brain dopamine transporter (DAT) inhibitor.
CAS:
204069-50-1
Formula:
C24H26Cl2N2O
Molecular Weight:
429.39
Purity:
0.98
SMILES:
Cl.[H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(Cl)cc1)c1cc(no1)-c1ccc(C)cc1)N2C
References
1. Andersen ML, Sawyer EK, Carroll FI, Howell LL. Influence of chronic dopamine transporter inhibition by RTI-336 on motor behavior, sleep, and hormone levels in rhesus monkeys. Exp Clin Psychopharmacol. 2012 Apr;20(2):77-83. doi: 10.1037/a0026034. Epub 2011 Oct 24. PubMed PMID: 22023668; PubMed Central PMCID: PMC3302935.
2. Czoty PW, Martelle JL, Carroll FI, Nader MA. Lower reinforcing strength of the phenyltropane cocaine analogs RTI-336 and RTI-177 compared to cocaine in nonhuman primates. Pharmacol Biochem Behav. 2010 Sep;96(3):274-8. doi: 10.1016/j.pbb.2010.05.017. Epub 2010 May 24. PubMed PMID: 20580733; PubMed Central PMCID: PMC2907452.
3. Hiranita T, Wilkinson DS, Hong WC, Zou MF, Kopajtic TA, Soto PL, Lupica CR, Newman AH, Katz JL. 2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter. J Pharmacol Exp Ther. 2014 May;349(2):297-309. doi: 10.1124/jpet.113.212738. Epub 2014 Feb 11. Erratum in: J Pharmacol Exp Ther. 2014 Jun 1;349(3):534. PubMed PMID: 24518035; PubMed Central PMCID: PMC3989806.
4. Haile CN, Zhang XY, Carroll FI, Kosten TA. Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter. Brain Res. 2005 Sep 7;1055(1-2):186-95. PubMed PMID: 16095575.