Rubratoxin A
| Code | Size | Price |
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| TAR-T26164-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rubratoxin A is a classical mycotoxin used as a PP2A-specific inhibitor.
CAS:
22467-31-8
Formula:
C26H32O11
Molecular Weight:
520.531
Purity:
0.98
SMILES:
CCCCCCC(O)C1C(O)C2=C(CC(CC3=C1C(=O)OC3O)C(O)C1CC=CC(=O)O1)C(=O)OC2=O
References
1. Ishida M, Takeya K, Miyazu M, Yoshida A, Takai A. Force-inhibiting effect of Ser/Thr protein phosphatase 2A inhibitors on bovine ciliary muscle. J Smooth Muscle Res. 2015;51:10-21. PubMed PMID: 26727726; PubMed Central PMCID: PMC5137268.
2. Wada S, Usami I, Umezawa Y, Inoue H, Ohba S, Someno T, Kawada M, Ikeda D. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis. Cancer Sci. 2010 Mar;101(3):743-50. doi: 10.1111/j.1349-7006.2009.01438.x. Epub 2009 Nov 14. PubMed PMID: 20028386.
3. Phillips TD, Hayes AW. Structural modification of polyfunctional rubratoxin B: effects on mammalian adenosine triphosphatase. J Environ Pathol Toxicol. 1979 Jan-Feb;2(3):853-60. PubMed PMID: 217944.
4. Unger PD, Hayes AW. High-pressure liquid chromatography of the mycotoxins, rubratoxins A and B, and its application to the analysis of urine and plasma for rubratoxin B. J Chromatogr. 1978 Jun 1;153(1):115-26. PubMed PMID: 580783.