S23757
| Code | Size | Price |
|---|
| TAR-T26171-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26171-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26171-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
S23757 is an imidazoline 1 receptor (I1R) selective ligand.
CAS:
208718-14-3
Formula:
C10H11FN2
Molecular Weight:
178.21
Purity:
0.98
SMILES:
Cc1ccc(F)c(c1)C1=NCCN1
References
1. Bousquet P, Greney H, Bruban V, Schann S, Ehrhardt JD, Monassier L, Feldman J. I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going? Ann N Y Acad Sci. 2003 Dec;1009:228-33. Review. PubMed PMID: 15028592.
2. Sy GY, Bruban V, Bousquet P, Feldman J. Nitric oxide discriminates the sites and mechanisms of action of centrally acting anti-hypertensive drugs in rabbits. Neuropharmacology. 2002 Dec;43(8):1330-8. PubMed PMID: 12527483.
3. Bruban V, Estato V, Schann S, Ehrhardt JD, Monassier L, Renard P, Scalbert E, Feldman J, Bousquet P. Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation. Circulation. 2002 Mar 5;105(9):1116-21. PubMed PMID: 11877365.
4. Bruban V, Feldman J, Greney H, Dontenwill M, Schann S, Jarry C, Payard M, Boutin J, Scalbert E, Pfeiffer B, Renard P, Vanhoutte P, Bousquet P. Respective contributions of alpha-adrenergic and non-adrenergic mechanisms in the hypotensive effect of imidazoline-like drugs. Br J Pharmacol. 2001 May;133(2):261-6. PubMed PMID: 11350862; PubMed Central PMCID: PMC1572786.