Septacidin
| Code | Size | Price |
|---|
| TAR-T26185-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Septacidin represents a group of l-eptopyranoses including nucleoside antibiotics with antitumor, antifungal, and pain-relief activities.
CAS:
62362-59-8
Formula:
C30H51N7O7
Molecular Weight:
621.78
Purity:
0.98
SMILES:
CC(C)CCCCCCCCCCCCC(=O)NCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](Nc2ncnc3[nH]cnc23)O[C@H]1[C@@H](O)CO
References
1. Tang W, Guo Z, Cao Z, Wang M, Li P, Meng X, Zhao X, Xie Z, Wang W, Zhou A, Lou C, Chen Y. d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2818-2823. doi: 10.1073/pnas.1711665115. Epub 2018 Feb 26. PubMed PMID: 29483275; PubMed Central PMCID: PMC5856511.
2. Sukkurwala AQ, Adjemian S, Senovilla L, Michaud M, Spaggiari S, Vacchelli E, Baracco EE, Galluzzi L, Zitvogel L, Kepp O, Kroemer G. Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set. Oncoimmunology. 2014 Apr 16;3:e28473. eCollection 2014. PubMed PMID: 25050214; PubMed Central PMCID: PMC4063139.
3. Price NP, Furukawa T, Cheng F, Qi J, Chen W, Crich D. Biosynthesis of 4-aminoheptose 2-epimers, core structural components of the septacidins and spicamycins. J Antibiot (Tokyo). 2014 May;67(5):405-14. doi: 10.1038/ja.2014.15. Epub 2014 Mar 19. PubMed PMID: 24643053.
4. Mizumura Y. [Spicamycin derivative]. Nihon Rinsho. 2006 Feb;64(2):322-8. Review. Japanese. PubMed PMID: 16454188.