SK&F 106760
| Code | Size | Price |
|---|
| TAR-T26190-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SKF 106760 is used as a glycoprotein IIb/IIIa antagonist.
CAS:
126053-71-2
Formula:
C23H39N9O8S2
Molecular Weight:
633.74
Purity:
0.98
SMILES:
CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N)=O)C(C)(C)SSC[C@H](NC(C)=O)C1=O
References
1. Willette RN, Sauermelch CF, Rycyna R, Sarkar S, Feuerstein GZ, Nichols AJ, Ohlstein EH. Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis. Stroke. 1992 May;23(5):703-11. PubMed PMID: 1605806.
2. Nichols AJ, Vasko JA, Valocik RE, Kopaciewicz LJ, Storer BL, Ali FE, Romoff T, Calvo R, Samanen JM. The in vitro pharmacological profile of SK&F 106760, a novel GPIIB/IIIA antagonist. Thromb Res. 1994 Jul 15;75(2):143-56. PubMed PMID: 7974388.
3. Nichols AJ, Vasko JA, Koster PF, Valocik RE, Rhodes GR, Miller-Stein C, Boppana V, Samanen JM. The in vivo pharmacological profile of the novel glycoprotein IIb/IIIa antagonist, SK&F 106760. J Pharmacol Exp Ther. 1994 Aug;270(2):614-21. PubMed PMID: 8071853.
4. Constantinides PP, Scalart JP, Lancaster C, Marcello J, Marks G, Ellens H, Smith PL. Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides. Pharm Res. 1994 Oct;11(10):1385-90. PubMed PMID: 7855039.