TargetMol

SK&F 106760

Product Code:
 
TAR-T26190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26190-5mg5mg£850.00
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Further Information

Bioactivity:
SKF 106760 is used as a glycoprotein IIb/IIIa antagonist.
CAS:
126053-71-2
Formula:
C23H39N9O8S2
Molecular Weight:
633.74
Purity:
0.98
SMILES:
CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N)=O)C(C)(C)SSC[C@H](NC(C)=O)C1=O

References

1. Willette RN, Sauermelch CF, Rycyna R, Sarkar S, Feuerstein GZ, Nichols AJ, Ohlstein EH. Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis. Stroke. 1992 May;23(5):703-11. PubMed PMID: 1605806. 2. Nichols AJ, Vasko JA, Valocik RE, Kopaciewicz LJ, Storer BL, Ali FE, Romoff T, Calvo R, Samanen JM. The in vitro pharmacological profile of SK&F 106760, a novel GPIIB/IIIA antagonist. Thromb Res. 1994 Jul 15;75(2):143-56. PubMed PMID: 7974388. 3. Nichols AJ, Vasko JA, Koster PF, Valocik RE, Rhodes GR, Miller-Stein C, Boppana V, Samanen JM. The in vivo pharmacological profile of the novel glycoprotein IIb/IIIa antagonist, SK&F 106760. J Pharmacol Exp Ther. 1994 Aug;270(2):614-21. PubMed PMID: 8071853. 4. Constantinides PP, Scalart JP, Lancaster C, Marcello J, Marks G, Ellens H, Smith PL. Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides. Pharm Res. 1994 Oct;11(10):1385-90. PubMed PMID: 7855039.