SP-Chymostatin B
Code | Size | Price |
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TAR-T26202-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26202-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26202-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. It is effective at a final concentration of 100 to 200 μg/ml (10 to 100 μM).
CAS:
70857-49-7
Formula:
C30H41N7O6
Molecular Weight:
595.701
Purity:
0.98
SMILES:
CC(C)[C@H](N([C@@H](Cc1ccccc1)C=O)C(=O)[C@H](CCCNC(N)=N)NC(=O)NC(Cc1ccccc1)C(O)=O)C(N)=O
References
1. Haas KM. B-1 lymphocytes in mice and nonhuman primates. Ann N Y Acad Sci. 2015 Dec;1362:98-109. doi: 10.1111/nyas.12760. Epub 2015 Apr 30. Review. PubMed PMID: 25930711; PubMed Central PMCID: PMC4627897.
2. Dickinson GS, Akkoyunlu M, Bram RJ, Alugupalli KR. BAFF receptor and TACI in B-1b cell maintenance and antibacterial responses. Ann N Y Acad Sci. 2015 Dec;1362:57-67. doi: 10.1111/nyas.12772. Epub 2015 May 11. Review. PubMed PMID: 25962322.
3. Popi AF. B-1 phagocytes: the myeloid face of B-1 cells. Ann N Y Acad Sci. 2015 Dec;1362:86-97. doi: 10.1111/nyas.12814. Epub 2015 Jul 6. Review. PubMed PMID: 26149496.
4. Yenson V, Baumgarth N. Purification and immune phenotyping of B-1 cells from body cavities of mice. Methods Mol Biol. 2014;1190:17-34. doi: 10.1007/978-1-4939-1161-5_2. PubMed PMID: 25015270.