TANDEM (quinoxaline)
| Code | Size | Price |
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| TAR-T26249-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TANDEM (quinoxaline) is a synthetic analog of antibiotics quinoxaline.
CAS:
63478-55-7
Formula:
C46H54N12O12S2
Molecular Weight:
1031.13
Purity:
0.98
SMILES:
CCC[C@@H]1NC(=O)[C@H]2CSSC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](COC1=O)NC(=O)c1cnc3ccccc3n1)C(=O)N[C@@H](CCC)C(=O)OC[C@H](NC(=O)c1cnc3ccccc3n1)C(=O)N[C@@H](C)C(=O)N2
References
1. Sung KW, Lim DH, Lee SH, Yoo KH, Koo HH, Kim JH, Suh YL, Joung YS, Shin HJ. Tandem high-dose chemotherapy and autologous stem cell transplantation for anaplastic ependymoma in children younger than 3 years of age. J Neurooncol. 2012 Apr;107(2):335-42. doi: 10.1007/s11060-011-0745-8. Epub 2011 Nov 12. PubMed PMID: 22081297.
2. Hampshire AJ, Rusling DA, Bryan S, Paumier D, Dawson SJ, Malkinson JP, Searcey M, Fox KR. DNA binding by analogues of the bifunctional intercalator TANDEM. Biochemistry. 2008 Jul 29;47(30):7900-6. doi: 10.1021/bi800573p. Epub 2008 Jul 3. PubMed PMID: 18597492.
3. Hampshire AJ, Fox KR. Preferred binding sites for the bifunctional intercalator TANDEM determined using DNA fragments that contain every symmetrical hexanucleotide sequence. Anal Biochem. 2008 Mar 15;374(2):298-303. Epub 2007 Oct 11. PubMed PMID: 17980140.
4. Hammond NB, Tolbert BS, Kierzek R, Turner DH, Kennedy SD. RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA. Biochemistry. 2010 Jul 13;49(27):5817-27. doi: 10.1021/bi100332r. PubMed PMID: 20481618; PubMed Central PMCID: PMC2900907.