Tetrahydrohomofolic acid
Code | Size | Price |
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TAR-T26261-5mg | 5mg | £1,572.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26261-50mg | 50mg | £3,107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26261-100mg | 100mg | £4,247.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Tetrahydrohomofolic acid is a thymidylate synthetase inhibitor, antibacterial, and antimalarial agent.
CAS:
5786-82-3
Formula:
C20H25N7O6
Molecular Weight:
459.463
Purity:
0.98
SMILES:
Nc1nc(O)c2NC(CCNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1
References
1. Slieker LJ, Benkovic SJ. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate. Mol Pharmacol. 1984 Mar;25(2):294-302. PubMed PMID: 6700575.
2. Wasserman GF, Benkovic PA, Young M, Benkovic SJ. Kinetic relationships between the various activities of the formyl-methenyl-methylenetetrahydrofolate synthetase. Biochemistry. 1983 Mar 1;22(5):1005-13. PubMed PMID: 6601493.
3. Fong KL, Ho DH, Benjamin RS, Yang F, Sickler J, Brown NS, Bodey GP. A radioimmunoassay for 5-methyltetrahydrohomofolate. J Pharmacol Exp Ther. 1981 Aug;218(2):344-7. PubMed PMID: 6265623.
4. Mishra LC, Mead JA. On the biochemical mechanism of action of tetrahydrohomofolic acid. Biochem Pharmacol. 1972 Feb 15;21(4):579-81. PubMed PMID: 5014514.