TargetMol

TYT-1

Product Code:
 
TAR-T26303
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26303-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26303-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26303-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
TYT-1 is the most effective WNV NS3 inhibitor reported to date.
CAS:
64803-10-7
Formula:
C21H17N3O2S3
Molecular Weight:
439.57
Purity:
0.98
SMILES:
O=S1(=O)CSC(=N/C(=S)N(c2ccccc2)c2ccccc2)N1c1ccccc1

References

1. Zhao Y, Quick M, Shi L, Mehler EL, Weinstein H, Javitch JA. Substrate-dependent proton antiport in neurotransmitter:sodium symporters. Nat Chem Biol. 2010 Feb;6(2):109-16. doi: 10.1038/nchembio.284. Epub 2009 Dec 27. PubMed PMID: 20081826; PubMed Central PMCID: PMC2808765. 2. Zomot E, Bendahan A, Quick M, Zhao Y, Javitch JA, Kanner BI. Mechanism of chloride interaction with neurotransmitter:sodium symporters. Nature. 2007 Oct 11;449(7163):726-30. Epub 2007 Aug 19. PubMed PMID: 17704762. 3. Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum. J Biol Chem. 2006 Sep 8;281(36):26444-54. Epub 2006 Jun 23. PubMed PMID: 16798738. 4. Maslov DL, Lokhov PG, Abakumova OY, Tsvetkova TA, Prozorovskiy VN. New peptidomimetics of insulin. J Biochem Mol Biol Biophys. 2002 Aug;6(4):261-5. PubMed PMID: 12186742.