YK5
| Code | Size | Price |
|---|
| TAR-T26343-5mg | 5mg | £1,251.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26343-50mg | 50mg | £2,464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26343-100mg | 100mg | £3,283.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
YK5 is an allosteric inhibitor pocket of Hsp70 and represents a previously unknown chemical tool to investigate cellular mechanisms associated with Hsp70.
CAS:
1268273-23-9
Formula:
C18H24N8O3S
Molecular Weight:
432.5
Purity:
0.98
SMILES:
COc1nc(nc(OC)c1Sc1nc(N)cc(NC(=O)C=C)n1)N1CCN(C)CC1
References
1. Kim JS, Jeong JH, Kim Y. Design and Engineering of Antimicrobial Peptides Based on LPcin-YK3, an Antimicrobial Peptide Derivative from Bovine Milk. J Microbiol Biotechnol. 2018 Mar 28;28(3):381-390. doi: 10.4014/jmb.1711.11057. PubMed PMID: 29316742.
2. Djegui KY, Gachomo EW, Hounhouigan DJ, Kayod? AP, Kotchoni SO. Biochemical characterization and growth patterns of new yeast isolates. Mol Biol Rep. 2014 Aug;41(8):5199-206. doi: 10.1007/s11033-014-3387-z. Epub 2014 May 7. PubMed PMID: 24802797.
3. Rodina A, Patel PD, Kang Y, Patel Y, Baaklini I, Wong MJ, Taldone T, Yan P, Yang C, Maharaj R, Gozman A, Patel MR, Patel HJ, Chirico W, Erdjument-Bromage H, Talele TT, Young JC, Chiosis G. Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein. Chem Biol. 2013 Dec 19;20(12):1469-80. doi: 10.1016/j.chembiol.2013.10.008. Epub 2013 Nov 14. PubMed PMID: 24239008; PubMed Central PMCID: PMC3985611.
4. Iida T, Nakamura K, Izumi A, Mukouzaka Y, Kudo T. Isolation and characterization of a gene cluster for dibenzofuran degradation in a new dibenzofuran-utilizing bacterium, Paenibacillus sp. strain YK5. Arch Microbiol. 2006 Jan;184(5):305-15. Epub 2005 Nov 12. PubMed PMID: 16284749.