(S)-alpha-Fluoromethylhistidine 2 HCl
| Code | Size | Price |
|---|
| TAR-T26374-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26374-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26374-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
(S)-alpha-Fluoromethylhistidine 2 HCl is a potent irreversible inhibitor of histidine decarboxylase (HDC) and glutathione S-transferase.
CAS:
81839-27-2
Formula:
C7H10FN3O2
Molecular Weight:
187.174
Purity:
0.98
SMILES:
N[C@@](CF)(Cc1cnc[nH]1)C(O)=O
References
1. Bencs?th M, P?l?czi K, Szalai C, Szenthe A, Szeber?nyi J, Falus A. Histidine decarboxylase in peripheral lymphocytes of healthy individuals and chronic lymphoid leukemia patients. Pathol Oncol Res. 1998;4(2):121-4. PubMed PMID: 9654597.
2. Vaziri P, Dang K, Anderson GH. Evidence for histamine involvement in the effect of histidine loads on food and water intake in rats. J Nutr. 1997 Aug;127(8):1519-26. PubMed PMID: 9237947.
3. Malmberg-Aiello P, Lamberti C, Ghelardini C, Giotti A, Bartolini A. Role of histamine in rodent antinociception. Br J Pharmacol. 1994 Apr;111(4):1269-79. PubMed PMID: 8032614; PubMed Central PMCID: PMC1910136.
4. Brandes LJ, Davie JR, Paraskevas F, Sukhu B, Bogdanovic RP, LaBella FS. The antiproliferative potency of histamine antagonists correlates with inhibition of binding of [3H]-histamine to novel intracellular receptors (HIC) in microsomal and nuclear fractions of rat liver. Agents Actions Suppl. 1991;33:325-42. PubMed PMID: 2053513.