7DG
| Code | Size | Price |
|---|
| TAR-T26398-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
7DG is a selective inhibitor of protein kinase R (PKR).
CAS:
26927-01-5
Formula:
C26H30O5
Molecular Weight:
422.521
Purity:
0.98
SMILES:
CC1(C)[C@@H]2C=C[C@]3(C)[C@H](CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@@]345)c3ccoc3)[C@@]2(C)C=CC1=O
References
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2. Kawanishi M, Fujikawa Y, Ishii H, Nishida H, Higashigaki Y, Kanno T, Matsuda T, Takamura-Enya T, Yagi T. Adduct formation and repair, and translesion DNA synthesis across the adducts in human cells exposed to 3-nitrobenzanthrone. Mutat Res. 2013 May 15;753(2):93-100. doi: 10.1016/j.mrgentox.2013.03.005. Epub 2013 Apr 6. PubMed PMID: 23567330.
3. Moeller BC, Recio L, Green A, Sun W, Wright FA, Bodnar WM, Swenberg JA. Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure. Toxicol Sci. 2013 May;133(1):1-12. doi: 10.1093/toxsci/kft029. Epub 2013 Feb 19. PubMed PMID: 23425604; PubMed Central PMCID: PMC3627555.
4. Lu K, Collins LB, Ru H, Bermudez E, Swenberg JA. Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia. Toxicol Sci. 2010 Aug;116(2):441-51. doi: 10.1093/toxsci/kfq061. Epub 2010 Feb 22. PubMed PMID: 20176625; PubMed Central PMCID: PMC2905397.