A 33853
| Code | Size | Price |
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| TAR-T26416-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
A 33853 is an antibiotic isolated from culture broth of Streptomyces sp.
CAS:
80148-45-4
Formula:
C20H13N3O6
Molecular Weight:
391.339
Purity:
0.98
SMILES:
OC(=O)c1cccc2oc(nc12)-c1cccc(O)c1NC(=O)c1ncccc1O
References
1. Michel KH, Boeck LD, Hoehn MM, Jones ND, Chaney MO. The discovery, fermentation, isolation, and structure of antibiotic A33853 and its tetraacetyl derivative. J Antibiot (Tokyo). 1984 May;37(5):441-5. PubMed PMID: 6547431.
2. Tipparaju SK, Joyasawal S, Pieroni M, Kaiser M, Brun R, Kozikowski AP. In pursuit of natural product leads: synthesis and biological evaluation of 2-[3 hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and its analogues: discovery of N-(2-benzoxazol2-ylphenyl)benzamides as novel antileishmanial chemotypes. J Med Chem. 2008 Dec 11;51(23):7344-7. doi: 10.1021/jm801241n. PubMed PMID: 18989953.
3. Lv M, Zhao J, Deng Z, Yu Y. Characterization of the Biosynthetic Gene Cluster for Benzoxazole Antibiotics A33853 Reveals Unusual Assembly Logic. Chem Biol. 2015 Oct 22;22(10):1313-24. doi: 10.1016/j.chembiol.2015.09.005. PubMed PMID: 26496684.