A 65281
Code | Size | Price |
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TAR-T26429-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26429-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26429-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
A 65281 is an antibacterial isothiazoloquinolone and a potent inhibitor of the P4-unknotting reaction. It induces considerable DNA breakage mediated by calf thymus topoisomerase II.
CAS:
111279-49-3
Formula:
C17H16F2N4O2S
Molecular Weight:
378.4
Purity:
0.98
SMILES:
Fc1cc2c(c(F)c1N1CCNCC1)n(C1CC1)c1s[nH]c(=O)c1c2=O
References
1. Kohlbrenner WE, Wideburg N, Weigl D, Saldivar A, Chu DT. Induction of calf thymus topoisomerase II-mediated DNA breakage by the antibacterial isothiazoloquinolones A-65281 and A-65282. Antimicrob Agents Chemother. 1992 Jan;36(1):81-6. PubMed PMID: 1317151; PubMed Central PMCID: PMC189231.