Antofloxacin Hydrochloride
| Code | Size | Price |
|---|
| TAR-T26638-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26638-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26638-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis.
CAS:
873888-67-6
Formula:
C18H22ClFN4O4
Molecular Weight:
412.85
Purity:
0.98
SMILES:
Cl.C[C@H]1COc2c(N3CCN(C)CC3)c(F)c(N)c3c2n1cc(C(O)=O)c3=O
References
1. Liu L, Pan X, Liu HY, Liu XD, Yang HW, Xie L, Cheng JL, Fan HW, Xiao DW. Modulation of pharmacokinetics of theophylline by antofloxacin, a novel 8-amino-fluoroquinolone, in humans. Acta Pharmacol Sin. 2011 Oct;32(10):1285-93. doi: 10.1038/aps.2011.78. PubMed PMID: 21892200; PubMed Central PMCID: PMC4010077.
2. Wang J, Xiao Y, Lu Y, Kang Z, Zhang M, Liu Y, Liang J, Zhang M, Li T. Pharmacokinetics of antofloxacin hydrochloride in healthy male subjects after multiple intravenous dose administration. Xenobiotica. 2011 Jul;41(7):561-6. doi: 10.3109/00498254.2011.565820. PubMed PMID: 21446836.
3. L? Y, Kang ZS, Zhu Y, Zhang M, Liu Y, Zhang M, Li TY, Xiao YH. Pharmacokinetic study of single and multiple oral dose administration of antofloxacin hydrochloride in healthy male volunteers. Chin Med J (Engl). 2011 Jan;124(2):242-5. PubMed PMID: 21362374.
4. Zhao J, Liu Y, Jiang X, Guo P, Xu Y, Zhang P, Ji T, Lin Z, Wang W. Effect of C-5 position on the photochemical properties and phototoxicity of antofloxacin and levofloxacin: A stable and transient study. J Photochem Photobiol B. 2016 Feb;155:122-9. doi: 10.1016/j.jphotobiol.2015.12.004. PubMed PMID: 26746788.