AZD4619
Code | Size | Price |
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TAR-T26716-5mg | 5mg | £1,091.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26716-50mg | 50mg | £2,143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26716-100mg | 100mg | £2,801.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AZD4619 is a potent, selective and reversible orally bioavailable agonist of PPARα receptor.
CAS:
1067247-60-2
Formula:
C27H30O6S2
Molecular Weight:
514.65
Purity:
0.98
SMILES:
Cc1ccc(CCSC(Cc2ccc(CCOc3ccc(OS(C)(=O)=O)cc3)cc2)C(O)=O)cc1
References
1. Thulin P, Bamberg K, Buler M, Dahl B, Glinghammar B. The peroxisome proliferator-activated receptor ? agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels. Int J Mol Med. 2016 Sep;38(3):961-8. doi: 10.3892/ijmm.2016.2681. PubMed PMID: 27430334.
2. Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B. PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):1-9. doi: 10.1016/j.taap.2008.03.007. PubMed PMID: 18455211.