BAY-Y-5959
| Code | Size | Price |
|---|
| TAR-T26746-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26746-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26746-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BAY-Y-5959, a calcium channel agonist, is used potentially for the treatment of arrhythmia, heart failure and myocardial.
CAS:
146136-94-9
Formula:
C26H24N4O2
Molecular Weight:
424.504
Purity:
0.98
SMILES:
CC(C)OC(=O)C1=C(N)NC(C)=C(C#N)[C@H]1c1cccc2ncc(cc12)-c1ccccc1
References
1. de Haan S, Greiser M, Harks E, Blaauw Y, van Hunnik A, Verheule S, Allessie M, Schotten U. AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat. Circulation. 2006 Sep 19;114(12):1234-42. Epub 2006 Aug 28. PubMed PMID: 16940189.
2. Takagi G, Asai K, Vatner SF, Kudej RK, Rossi F, Peppas A, Takagi I, Resuello RR, Natividad F, Shen YT, Vatner DE. Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys. Am J Physiol Heart Circ Physiol. 2003 Aug;285(2):H527-34. PubMed PMID: 12860563.
3. Schotten U, Duytschaever M, Ausma J, Eijsbouts S, Neuberger HR, Allessie M. Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand. Circulation. 2003 Mar 18;107(10):1433-9. PubMed PMID: 12642366.
4. Cabo C, Schmitt H, Wit AL. New mechanism of antiarrhythmic drug action: increasing L-type calcium current prevents reentrant ventricular tachycardia in the infarcted canine heart. Circulation. 2000 Nov 7;102(19):2417-25. PubMed PMID: 11067798.