Binedaline
Code | Size | Price |
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TAR-T26818-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26818-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26818-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Binedaline is a selective norepinephrine reuptake inhibitor with Ki value of 25 nM.
CAS:
60662-16-0
Formula:
C19H23N3
Molecular Weight:
293.414
Purity:
0.98
SMILES:
CN(C)CCN(C)n1cc(-c2ccccc2)c2ccccc12
References
1. Saini T, Kumar S, Narasimhan B. Central Nervous System Activities of Indole Derivatives: An Overview. Cent Nerv Syst Agents Med Chem. 2015;16(1):19-28. Review. PubMed PMID: 26051466.
2. Simon N, Dailly E, Jolliet P, Tillement JP, Urien S. pH dependent binding of ligands to serum lipoproteins. Pharm Res. 1997 Apr;14(4):527-32. PubMed PMID: 9144744.
3. Urien S, Giroud Y, Tsai RS, Carrupt PA, Br?e F, Testa B, Tillement JP. Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity. Biochem J. 1995 Mar 1;306 ( Pt 2):545-9. PubMed PMID: 7887909; PubMed Central PMCID: PMC1136552.
4. Morin D, Zini R, Urien S, Tillement JP. Pharmacological profile of binedaline, a new antidepressant drug. J Pharmacol Exp Ther. 1989 Apr;249(1):288-96. PubMed PMID: 2540319.