BKM1644
| Code | Size | Price |
|---|
| TAR-T26831-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.
CAS:
1070966-96-9
Formula:
C34H37Cl2F5N2O9P2
Molecular Weight:
845.51
Purity:
0.98
SMILES:
CCOP(=O)(OCC)C(NC(=O)[C@@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C=Cc1c(F)c(F)c(F)c(F)c1F)P(=O)(OCC)OCC
References
1. Zhang S, Gera L, Mamouni K, Li X, Chen Z, Kucuk O, Wu D. Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative. Oncotarget. 2016 May 10;7(19):27489-98. doi: 10.18632/oncotarget.8481. PubMed PMID: 27050371; PubMed Central PMCID: PMC5053666.