BMS-561390

TargetMol
Product Code: TAR-T26851
Supplier: TargetMol
CodeSizePrice
TAR-T26851-5mg5mg£1,010.00
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Quantity:
TAR-T26851-50mg50mg£1,982.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26851-100mg100mg£2,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
CAS:
214287-99-7
Formula:
C14H12ClF3N2O
Molecular Weight:
316.71
Purity:
0.98
SMILES:
FC(F)(F)[C@]1(NC(=O)Nc2ccc(Cl)cc12)C=CC1CC1

References

1. Li S, Ma JA. Core-structure-inspired asymmetric addition reactions: enantioselective synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents. Chem Soc Rev. 2015 Nov 7;44(21):7439-48. doi: 10.1039/c5cs00342c. Review. PubMed PMID: 26177889. 2. Bindra DS, Desikan S. Impact of micromeritic properties of an active pharmaceutical ingredient on its compaction behavior. Pharm Dev Technol. 2015 Mar;20(2):129-38. doi: 10.3109/10837450.2013.852569. PubMed PMID: 24219704. 3. Yuan HN, Li S, Nie J, Zheng Y, Ma JA. Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of ?-amino esters and anti-HIV drug DPC 083. Chemistry. 2013 Nov 18;19(47):15856-60. doi: 10.1002/chem.201303307. PubMed PMID: 24150893. 4. Yuan HN, Wang S, Nie J, Meng W, Yao Q, Ma JA. Hydrogen-bond-directed enantioselective decarboxylative Mannich reaction of ?-ketoacids with ketimines: application to the synthesis of anti-HIV drug DPC 083. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3869-73. doi: 10.1002/anie.201210361. PubMed PMID: 23460261.