BNC-1
Code | Size | Price |
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TAR-T26879-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26879-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26879-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
BNC-1 is a modulator of amyloid pathology. BNC-1 significantly decreases amyloid burden and improves markers of synaptic integrity in well-established mouse models of amyloid deposition by promoting phosphorylation and activation of Elk-1.
CAS:
96335-59-0
Formula:
C16H14N2O3
Molecular Weight:
282.299
Purity:
0.98
SMILES:
COC(=O)c1c(C)nc(C)c2c1c1ccccc1[nH]c2=O
References
1. Lovell MA, Lynn BC, Fister S, Bradley-Whitman M, Murphy MP, Beckett TL, Norris CM. A Novel Small Molecule Modulator of Amyloid Pathology. J Alzheimers Dis. 2016 May 4;53(1):273-87. doi: 10.3233/JAD-151160. PubMed PMID: 27163808.
2. Hermanstyne TO, Markowitz K, Fan L, Gold MS. Mechanotransducers in rat pulpal afferents. J Dent Res. 2008 Sep;87(9):834-8. PubMed PMID: 18719209; PubMed Central PMCID: PMC2577312.
3. Wang J, Zhang S, Schultz RM, Tseng H. Search for basonuclin target genes. Biochem Biophys Res Commun. 2006 Oct 6;348(4):1261-71. Epub 2006 Aug 10. PubMed PMID: 16919236; PubMed Central PMCID: PMC1630671.
4. DeSimone JA, Lyall V, Heck GL, Feldman GM. Acid detection by taste receptor cells. Respir Physiol. 2001 Dec;129(1-2):231-45. Review. PubMed PMID: 11738657.