Bremazocine
| Code | Size | Price |
|---|
| TAR-T26902-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bremazocineis a potent opiate kappa-agonist and centrally acting analgesic.
CAS:
75684-07-0
Formula:
C20H29NO2
Molecular Weight:
315.457
Purity:
0.98
SMILES:
[H][C@]12Cc3ccc(O)cc3C(CC)(CCN1CC1(O)CC1)C2(C)C
References
1. Petrillo P, Gambino MC, Tavani A. Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats. Life Sci. 1984 Aug 27;35(9):917-27. PubMed PMID: 6381949.
2. Simonin F, Slowe S, Becker JA, Matthes HW, Filliol D, Chluba J, Kitchen I, Kieffer BL. Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice. Eur J Pharmacol. 2001 Mar 2;414(2-3):189-95. PubMed PMID: 11239918.
3. Dortch-Carnes J, Potter DE. Bremazocine: a kappa-opioid agonist with potent analgesic and other pharmacologic properties. CNS Drug Rev. 2005 Summer;11(2):195-212. Review. PubMed PMID: 16007240.
4. Shearman GT, Stenfors C. Bremazocine-induced backwards walking behavior in rats is mediated via opioid kappa receptors. Pharmacol Biochem Behav. 1986 Apr;24(4):861-3. PubMed PMID: 3012599.