BRL 55834
| Code | Size | Price |
|---|
| TAR-T26905-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26905-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26905-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BRL 55834, a potassium channel activator, has shown to relax airways and vasculature in vivo.
CAS:
131899-25-7
Formula:
C18H20F5NO3
Molecular Weight:
393.354
Purity:
0.98
SMILES:
CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCCC1=O)C(F)(F)C(F)(F)F
References
1. Bowring NE, Arch JR, Buckle DR, Taylor JF. Comparison of the airways relaxant and hypotensive potencies of the potassium channel activators BRL 55834 and levcromakalim (BRL 38227) in vivo in guinea-pigs and rats. Br J Pharmacol. 1993 Aug;109(4):1133-9. PubMed PMID: 8401925; PubMed Central PMCID: PMC2175747.
2. Arch JR, Bowring NE, Buckle DR. Evaluation of the novel potassium channel activator BRL 55834 as an inhaled bronchodilator in guinea-pigs and rats: comparison with levcromakalim and salbutamol. Pulm Pharmacol. 1994 Apr;7(2):121-8. PubMed PMID: 8081072.
3. Shi Z, Yan Z, Luo W. [Antigen-induced airway leakage in asthmatic guinea-pigs and the effects of BRL 55834]. Zhonghua Jie He He Hu Xi Za Zhi. 1998 Apr;21(4):229-32. Chinese. PubMed PMID: 11326971.
4. Shi Z, Luo W, Xiu Q, Ye Y, Yan Z, Zhu Q. Effects of BRL 55 834 on allergen-induced bronchoconstriction and airway inflammation in sensitized guinea pigs. Chin Med J (Engl). 1999 Nov;112(11):988-91. PubMed PMID: 11721481.