CD-349
Code | Size | Price |
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TAR-T26970-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26970-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26970-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CD-349 is a calcium channel antagonist. CD-349 inhibits the noradrenaline (NA)-induced contraction of aortas in Ca2(+)-free medium.
CAS:
88594-08-5
Formula:
C21H24N4O12
Molecular Weight:
524.439
Purity:
0.98
SMILES:
CC(COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCO[N+]([O-])=O)O[N+]([O-])=O
References
1. Miyata N, Yamaura H, Tsuchida K, Otomo S, Miyajima E. Role of cyclic GMP in inhibitory effects of CD-349 in isolated blood vessels. Gen Pharmacol. 1994 Mar;25(2):267-73. PubMed PMID: 8026725.
2. Ogawa N, Mizuno K, Fukushima K, Suwa T, Satoh T. Metabolic fate of a new dihydropyridine calcium antagonist, CD-349, in rat and dog. Xenobiotica. 1993 Jul;23(7):747-59. PubMed PMID: 8237057.
3. Ogawa T, Nakazato A, Tsuchida K, Hatayama K. Synthesis and antihypertensive activities of new 1,4-dihydropyridine derivatives containing nitrooxyalkylester moieties at the 3- and 5-positions. Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1049-54. PubMed PMID: 8370105.
4. Satoh H, Tsuchida K. Comparison of a calcium antagonist, CD-349, with nifedipine, diltiazem, and verapamil in rabbit spontaneously beating sinoatrial node cells. J Cardiovasc Pharmacol. 1993 May;21(5):685-92. PubMed PMID: 7685436.