Cefatrizine
| Code | Size | Price |
|---|
| TAR-T26973-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cefatrizine is an inhibitor of eukaryotic elongation factor-2 kinase, a unique calcium/calmodulin-dependent protein kinase, is well known to regulate apoptosis, autophagy and ER stress in many types of human cancers.
CAS:
51627-14-6
Formula:
C18H18N6O5S2
Molecular Weight:
462.5
Purity:
0.98
SMILES:
[H][C@]12SCC(CSc3c[nH]nn3)=C(N1C(=O)[C@H]2NC(=O)C(N)c1ccc(O)cc1)C(O)=O
References
1. Pan J, Wang L, Li D, Ye L. [Synthesis of cefatrizine by recombinant alpha-amino acid ester hydrolase]. Sheng Wu Gong Cheng Xue Bao. 2013 Apr;29(4):501-9. Chinese. PubMed PMID: 23894823.
2. Papantoniou N, Ismailos G, Daskalakis G, Karabinas C, Mesogitis S, Papapanagiotou A, Antsaklis A. Pharmacokinetics of oral cefatrizine in pregnant and non-pregnant women with reference to fetal distribution. Fetal Diagn Ther. 2007;22(2):100-6. PubMed PMID: 17135753.
3. Choi HG, Jun HW, Kim DD, Sah H, Yoo BK, Yong CS. Simultaneous determination of cefatrizine and clavulanic acid in dog plasma by HPLC. J Pharm Biomed Anal. 2004 Apr 1;35(1):221-31. PubMed PMID: 15030898.
4. Sultana N, Arayne MS. In vitro activity of cefadroxil, cephalexin, cefatrizine and cefpirome in presence of essential and trace elements. Pak J Pharm Sci. 2007 Oct;20(4):305-10. PubMed PMID: 17604254.