CGS-12066 maleate salt
Code | Size | Price |
---|
TAR-T27000-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27000-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27000-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CGS-12066 maleate salt is an agonist of 5-HT1B serotonin receptor.
CAS:
1350965-83-1
Formula:
C21H21F3N4O4
Molecular Weight:
450.418
Purity:
0.98
SMILES:
OC(=O)C=C/C(O)=O.CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F
References
1. Garc?a-Pedraza J?, Garc?a M, Mart?n ML, Mor?n A. 5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats. Vascul Pharmacol. 2015 Sep;72:172-80. doi: 10.1016/j.vph.2015.05.003. PubMed PMID: 26003124.
2. Garc?a-Pedraza JA, Garc?a M, Mart?n ML, Rodr?guez-Barbero A, Mor?n A. 5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature. Vascul Pharmacol. 2016 Apr;79:51-9. doi: 10.1016/j.vph.2015.11.039. PubMed PMID: 26586311.
3. Garc?a-Pedraza J?, Garc?a M, Mart?n ML, Mor?n A. Pharmacological evidence that 5-HT1D activation induces renal vasodilation by NO pathway in rats. Clin Exp Pharmacol Physiol. 2015 Jun;42(6):640-7. doi: 10.1111/1440-1681.12397. PubMed PMID: 25854421.