CNS-5161
Code | Size | Price |
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TAR-T27055-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27055-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27055-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CNS-5161 is an NMDA antagonist.
CAS:
160754-76-7
Formula:
C16H18ClN3S2
Molecular Weight:
351.91
Purity:
0.98
SMILES:
CSc1cccc(c1)N(C)C(=N)Nc1cc(SC)ccc1Cl
References
1. Biegon A, Gibbs A, Alvarado M, Ono M, Taylor S. In vitro and in vivo characterization of [3H]CNS-5161--a use-dependent ligand for the N-methyl-D-aspartate receptor in rat brain. Synapse. 2007 Aug;61(8):577-86. PubMed PMID: 17455246.
2. Forst T, Smith T, Sch?tte K, Marcus P, Pf?tzner A; CNS 5161 Study Group.. Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain. Br J Clin Pharmacol. 2007 Jul;64(1):75-82. PubMed PMID: 17391323; PubMed Central PMCID: PMC2000615.
3. Walters MR, Bradford AP, Fischer J, Lees KR. Early clinical experience with the novel NMDA receptor antagonist CNS 5161. Br J Clin Pharmacol. 2002 Mar;53(3):305-11. PubMed PMID: 11874394; PubMed Central PMCID: PMC1874317.
4. McGinnity CJ, Hammers A, Ria?o Barros DA, Luthra SK, Jones PA, Trigg W, Micallef C, Symms MR, Brooks DJ, Koepp MJ, Duncan JS. Initial evaluation of 18F-GE-179, a putative PET Tracer for activated N-methyl D-aspartate receptors. J Nucl Med. 2014 Mar;55(3):423-30. doi: 10.2967/jnumed.113.130641. PubMed PMID: 24525206.