CV-3988
| Code | Size | Price |
|---|
| TAR-T27101-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27101-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27101-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CV-3988 is a specific antagonist of PAF-R (platelet-activating factor receptor)(Ki = 0.872 μM).
CAS:
85703-73-7
Formula:
C28H53N2O7PS
Molecular Weight:
592.77
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP([O-])(=O)OCC[n+]1ccsc1)OC
References
1. Lee CM, Jung WK, Na G, Lee DS, Park SG, Seo SK, Yang JW, Yea SS, Lee YM, Park WS, Choi IW. Inhibitory effects of the platelet-activating factor receptor antagonists, CV-3988 and Ginkgolide B, on alkali burn-induced corneal neovascularization. Cutan Ocul Toxicol. 2015 Mar;34(1):53-60. doi: 10.3109/15569527.2014.903573. PubMed PMID: 24754407.
2. Okano S, Tagawa M, Urakawa N. Effect of platelet activating factor antagonist (CV-3988) on 6-keto-PGF1 alpha and thromboxane B2 in dogs with experimental endotoxin-induced shock. J Vet Med Sci. 1995 Feb;57(1):81-5. PubMed PMID: 7756431.
3. Sawa Y, Schaper J, Roth M, Nagasawa K, Ballagi G, Bleese N, Schaper W. Platelet-activating factor plays an important role in reperfusion injury in myocardium. Efficacy of platelet-activating factor receptor antagonist (CV-3988) as compared with leukocyte-depleted reperfusion. J Thorac Cardiovasc Surg. 1994 Nov;108(5):953-9. PubMed PMID: 7967680.