10-Nitrooleic acid
Code | Size | Price |
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TAR-T27103-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27103-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27103-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CXA-10 is an endogenous nitro-fatty acid (NFA) modulator of Nrf2 and NF-κB. CXA-10 upregulates expression of caveolin-1, the major structural component of caveolae.
CAS:
875685-46-4
Formula:
C18H33NO4
Molecular Weight:
327.465
Purity:
0.98
SMILES:
CCCCCCCCC(=C/CCCCCCCC(O)=O)[N+]([O-])=O
References
1. Zheng R, Heck DE, Black AT, Gow A, Laskin DL, Laskin JD. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med. 2014 Feb;67:1-9. doi: 10.1016/j.freeradbiomed.2013.10.011. PubMed PMID: 24140437; PubMed Central PMCID: PMC4391631.
2. Gorczynski MJ, Smitherman PK, Akiyama TE, Wood HB, Berger JP, King SB, Morrow CS. Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by nitroalkene fatty acids: importance of nitration position and degree of unsaturation. J Med Chem. 2009 Aug 13;52(15):4631-9. doi: 10.1021/jm900326c. PubMed PMID: 19719236; PubMed Central PMCID: PMC2741172.