DHNQ
| Code | Size | Price |
|---|
| TAR-T27163-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27163-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27163-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).
CAS:
31785-60-1
Formula:
C18H14N2O
Molecular Weight:
274.323
Purity:
0.98
SMILES:
O=C1NC(Nc2ccccc12)c1cccc2ccccc12
References
1. Zwirchmayr NS, Hosoya T, Henniges U, Gille L, Bacher M, Furtm?ller P, Rosenau T. Degradation of the Cellulosic Key Chromophore 5,8-Dihydroxy-[1,4]-naphthoquinone by Hydrogen Peroxide under Alkaline Conditions. J Org Chem. 2017 Nov 3;82(21):11558-11565. doi: 10.1021/acs.joc.7b01827. PubMed PMID: 28968096.
2. Ajibola Adeyemo A, Shettar A, Bhat IA, Kondaiah P, Mukherjee PS. Self-Assembly of Discrete Ru(II)(8) Molecular Cages and Their in Vitro Anticancer Activity. Inorg Chem. 2017 Jan 3;56(1):608-617. doi: 10.1021/acs.inorgchem.6b02488. Epub 2016 Dec 20. PubMed PMID: 27997153.
3. Hussain A, Qazi AK, Mupparapu N, Guru SK, Kumar A, Sharma PR, Singh SK, Singh P, Dar MJ, Bharate SB, Zargar MA, Ahmed QN, Bhushan S, Vishwakarma RA, Hamid A. Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth. Cancer Lett. 2016 May 1;374(2):250-60. doi: 10.1016/j.canlet.2016.02.030. Epub 2016 Feb 23. PubMed PMID: 26921131.
4. Hussain A, Qazi AK, Mupparapu N, Kumar A, Mintoo MJ, Mahajan G, Sharma PR, Singh SK, Bharate SB, Zargar MA, Ahmed QN, Mondhe DM, Vishwakarma RA, Hamid A. A novel PI3K axis selective molecule exhibits potent tumor inhibition in colorectal carcinogenesis. Mol Carcinog. 2016 Dec;55(12):2135-2155. doi: 10.1002/mc.22457. Epub 2016 Jan 13. PubMed PMID: 26764221.