DPC-961
| Code | Size | Price |
|---|
| TAR-T27203-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27203-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27203-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
CAS:
214287-88-4
Formula:
C14H10ClF3N2O
Molecular Weight:
314.69
Purity:
0.98
SMILES:
FC(F)(F)[C@]1(NC(=O)Nc2ccc(Cl)cc12)C#CC1CC1
References
1. Li S, Ma JA. Core-structure-inspired asymmetric addition reactions: enantioselective synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents. Chem Soc Rev. 2015 Nov 7;44(21):7439-48. doi: 10.1039/c5cs00342c. Review. PubMed PMID: 26177889.
2. Otake K, Azukizawa S, Fukui M, Shibabayashi M, Kamemoto H, Miike T, Kunishiro K, Kasai M, Shirahase H. A novel series of (S)-2,7-substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: peroxisome proliferator-activated receptor ?/? dual agonists with protein-tyrosine phosphatase 1B inhibitory activity. Chem Pharm Bull (Tokyo). 2011;59(10):1233-42. PubMed PMID: 21963632.
3. Duchowicz PR, Fern?ndez M, Caballero J, Castro EA, Fern?ndez FM. QSAR for non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem. 2006 Sep 1;14(17):5876-89. PubMed PMID: 16766190.
4. Magnus NA, Confalone PN, Storace L, Patel M, Wood CC, Davis WP, Parsons RL Jr. General scope of 1,4-diastereoselective additions to a 2(3H)-quinazolinone: practical preparation of HIV therapeutics. J Org Chem. 2003 Feb 7;68(3):754-61. PubMed PMID: 12558396.