E-5842 (Citrate)
| Code | Size | Price |
|---|
| TAR-T27232-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27232-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27232-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
E-5842 (Citrate), an opioid receptor agonist, is used potentially for the treatment of psychotic disorders.
CAS:
220120-14-9
Formula:
C23H29FN4O7
Molecular Weight:
492.504
Purity:
0.98
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.Fc1ccc(cc1)C1=CCN(CCCCn2cncn2)CC1
References
1. Guzm?n A, Mar?n AP, Garc?a C, Fern?ndez de Henestrosa AR, Ruiz MT, Tortajada A, Marcos R. Induction of hypothermic conditions associated with increased micronuclei formation in sigma-1 receptor knockout mice after administration of the antipsychotic compound E-5842. Environ Mol Mutagen. 2008 Dec;49(9):727-33. doi: 10.1002/em.20428. PubMed PMID: 18800345.
2. Guzm?n A, Garc?a C, Fern?ndez de Henestrosa AR, Riley S, Ruiz MT, Mar?n AP, Tortajada A. Assessment of the genotoxic potential of the antipsychotic sigma receptor ligand E-5842. Mutat Res. 2006 Jun 16;605(1-2):63-77. PubMed PMID: 16677850.
3. Guzm?n A, Garc?a C, Mar?n AP, Ruiz MT, Tortajada A, Fern?ndez de Henestrosa AR. Induction of micronuclei in mouse bone-marrow erythrocytes in association with hypothermia after administration of the sigma receptor ligand E-5842. Mutat Res. 2004 Dec 31;565(1):11-22. PubMed PMID: 15576235.
4. Romero G, P?rez MP, Carceller A, Monroy X, Farr? AJ, Guitart X. Changes in phosphoinositide signalling activity and levels of the alpha subunit of G(q/11) protein in rat brain induced by E-5842, a sigma(1) receptor ligand and potential atypical antipsychotic. Neurosci Lett. 2000 Sep 1;290(3):189-92. PubMed PMID: 10963895.