TargetMol

Ebselen oxide

Product Code:
 
TAR-T27235
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27235-5mg5mg£503.00
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TAR-T27235-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27235-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Ebselen oxide is a dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9.
CAS:
104473-83-8
Formula:
C13H9NO2Se
Molecular Weight:
290.191
Purity:
0.98
SMILES:
O=C1N(c2ccccc2)[Se](=O)c2ccccc12

References

1. Wang Y, Wallach J, Duane S, Wang Y, Wu J, Wang J, Adejare A, Ma H. Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs. Drug Des Devel Ther. 2017 May 2;11:1369-1382. doi: 10.2147/DDDT.S124977. eCollection 2017. PubMed PMID: 28496307; PubMed Central PMCID: PMC5422321. 2. Mu?oz M, L?pez-Oliva ME, Pinilla E, Mart?nez MP, S?nchez A, Rodr?guez C, Garc?a-Sacrist?n A, Hern?ndez M, Rivera L, Prieto D. CYP epoxygenase-derived H(2)O(2) is involved in the endothelium-derived hyperpolarization (EDH) and relaxation of intrarenal arteries. Free Radic Biol Med. 2017 May;106:168-183. doi: 10.1016/j.freeradbiomed.2017.02.031. Epub 2017 Feb 14. PubMed PMID: 28212823. 3. Babiker FA, Al-Jarallah A, Joseph S. Understanding pacing postconditioning-mediated cardiac protection: a role of oxidative stress and a synergistic effect of adenosine. J Physiol Biochem. 2017 May;73(2):175-185. doi: 10.1007/s13105-016-0535-z. Epub 2016 Nov 19. PubMed PMID: 27864790. 4. Padiadpu J, Baloni P, Anand K, Munshi M, Thakur C, Mohan A, Singh A, Chandra N. Identifying and Tackling Emergent Vulnerability in Drug-Resistant Mycobacteria. ACS Infect Dis. 2016 Sep 9;2(9):592-607. Epub 2016 Aug 8. PubMed PMID: 27759382.