Emitefur
| Code | Size | Price |
|---|
| TAR-T27259-5mg | 5mg | £790.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27259-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27259-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Emitefur is a 5-fluorouracil derivative antitumor drug.
CAS:
110690-43-2
Formula:
C28H19FN4O8
Molecular Weight:
558.478
Purity:
0.98
SMILES:
CCOCn1cc(F)c(=O)n(C(=O)c2cccc(c2)C(=O)Oc2nc(OC(=O)c3ccccc3)ccc2C#N)c1=O
References
1. Shibahara T, Kaneko E, Itoh T, Awogi T, Tsushimoto G, Takahashi N, Marshall RR, Kirkland DJ. Mutagenic and clastogenic properties of (3-[3-(6-benzoyloxy-3-cyano-2- pyridyloxycarbonyl) benzoyl]-1-ethoxymethyl-5-fluorouracil) (BOF-A2), a new 5-fluorouracil derivative with anti-tumour activity. J Toxicol Sci. 1993 Aug;18 Suppl 3:11-9. PubMed PMID: 8258847.
2. Sugimachi K, Maehara Y. A phase II trial of a new 5-fluorouracil derivative, BOF-A2 (Emitefur), for patients with advanced gastric cancer. Surg Today. 2000;30(12):1067-72. PubMed PMID: 11193737.
3. Shibamoto Y, Murata R, Miyauchi S, Hirohashi M, Takagi T, Sasai K, Shibata T, Oya N, Takahashi M. Combined effect of clinically relevant doses of emitefur, a new 5-fluorouracil derivative, and radiation in murine tumours. Br J Cancer. 1996 Dec;74(11):1709-13. PubMed PMID: 8956782; PubMed Central PMCID: PMC2077217.
4. Fujita F, Fujita M, Sakamoto Y, Taguchi T. [Antitumor activity of combination treatment of BOF-A2 with CDDP against human lung cancers xenografted in nude mice]. Gan To Kagaku Ryoho. 1993 Feb;20(2):215-21. Japanese. PubMed PMID: 8382036.